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Low serum phosphate and magnesium levels are associated with peripheral neuropathy in patients with type 2 diabetes mellitus

Diabetes Research and Clinical Practice Dec 16, 2018

Zhang Q, et al. - Researchers involved 254 subjects to ascertain the correlation of serum phosphate, serum magnesium, and peripheral nerve function in type 2 diabetes mellitus (T2DM) cases. They used electromyography to analyze peripheral nerve function, created composite z scores of conduction velocity (CV), latency, and amplitude, and obtained demographic, medical and laboratory data. They observed lower levels of serum phosphate and serum magnesium in cases with diabetic peripheral neuropathy (DPN). A positive association was found between composite z score of CV and serum phosphate levels. Composite z score of amplitude and CV were observed related positively to serum magnesium levels. They also remarked the endurance of observed associations even after adjusting the potentially related factors eg, age, gender, smoking, diabetes duration etc.
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