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Longitudinal changes in fasting plasma glucose are associated with risk of cancer mortality: A Chinese cohort study

Cancer Medicine Jun 24, 2021

Wu M, Lu J, Yang Z, et al. - Since numerous studies have suggested that fasting plasma glucose (FPG) was correlated with the risk of mortality, but the relationship on longitudinal changes of FPG with the risk of mortality remained inconsistent, researchers investigated the association of FPG at baseline and its longitudinal changes with risk of mortality using data from a cohort study conducted in Yinzhou, China, from 2010 to 2018. Cox regression models and competing risk models were separately used to investigate the correlation of FPG levels and long-term fluctuation with risk of total and cause-specific mortality. The authors discovered that long-term fluctuations in FPG were significantly associated with the risk of total and cancer mortality in this cohort study. The findings imply that long-term fluctuations in FPG could be used as an effective indicator for predicting the risk of mortality in the future.

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