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Long-term trends of BMI and cardiometabolic risk factors among adults with type 1 diabetes: An observational study from the German/Austrian DPV registry

Diabetes Research and Clinical Practice Jul 27, 2021

Welters A, Tittel SR, Laubner K, et al. - The researchers wanted to look at time trends in BMI, obesity and cardiometabolic risk in adults with type 1 diabetes (T1DM) from the Diabetes Prospective Follow-up registry DPV. Data from 62,519 T1DM patients (age ≥ 18 years, BMI ≥ 18.5 kg/m 2) were analyzed. Multivariable regression models were used to determine time trends in BMI, obesity, and cardiometabolic risk, as well as predictors of increasing BMI. Individuals with T1DM's mean BMI increased from 25.0 kg/m 2 to 26.2 kg/m 2 between 1999 and 2018. This trend was most pronounced in young and middle-aged people (> 21-55 years of age), as well as those with higher baseline BMI. Diabetes duration and insulin dose were linked to an increase in BMI. Obesity is becoming more prevalent in adults with T1DM than in the general population in Germany. BMI should be closely monitored, especially during young adulthood, and cardiovascular risk factors should be better controlled to prevent CVD and premature death.

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