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Long-term survival in patients with post-LVAD right ventricular failure: Multi-state modelling with competing outcomes of heart transplant

The Journal of Heart and Lung Transplantation May 21, 2021

Shad R, Fong R, Quach N, et al. - Researchers sought to compare the results of LVAD patients who experienced postoperative RV failure accounting for the transitional probability of receiving an interim heart transplantation. They analyzed a retrospective cohort consisting of LVAD patients sourced from multiple high-volume centers based in the United States. There were 897 patients overall, 238 (26.5%) of these developed postoperative RV failure at index hospitalization. Significantly higher mortality in relation to long-term durable mechanical circulatory support was observed in patients who developed postoperative RV failure. Improving results may necessitate expeditious bridge to heart transplant wherever suitable, as well as critical reevaluation of organ allocation policies.

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