Krasniqi L, et al. - Among patients receiving solitary surgical aortic valve replacement with a Carpentier-Edwards Perimount bioprosthetic in Western Denmark, this investigation was carried out to determine the long-term survival, risk of reoperation as well as clinical results. This study included 1,604 patients with a median age of 73 years (IQR: 69–78). The estimated in-hospital mortality and 30-day mortality were 2.7% and 3.4%, respectively. The 5-, 10- and 15-year survival from all-cause mortality was noted to be 77, 52 and 24%, respectively. Following 10 years, survival without major adverse cardiovascular and cerebral events was reported to be 80%. Small valves, smoking and EuroSCORE II ≥4%, were revealed as significant risk factors of mortality. Post-7.5 years, reoperation risk was estimated to be < 5%, and valve prosthesis-patient mismatch and EuroSCORE II ≥4% were identified as significant risk factors. Overall, findings revealed a very satisfying long-term survival of patients receiving aortic valve replacement with a Carpentier-Edwards Perimount valve.