Long-term results of surgery compared with nonoperative treatment for lumbar degenerative spondylolisthesis in the Spine Patient Outcomes Research Trial (SPORT)
Spine Nov 19, 2018
Abdu WA, et al. - Experts compared the 8-year outcomes between surgery and nonoperative care and among different fusion techniques for symptomatic lumbar degenerative spondylolisthesis (DS). They enrolled the surgical candidates with DS from 13 centers with at least 12 weeks of symptoms and confirmatory imaging in a randomized controlled trial (RCT) or observational cohort study (OBS). Significantly greater improvements in pain and function for patients with symptomatic DS were seen in the patients who received surgery compared with nonoperative treatment through 8 years of follow-up. The outcomes were not affected by the fusion technique. Similar outcomes were noted among patients treated with uninstrumented posterolateral fusion, instrumented posterolateral fusion, and 360° fusion.
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