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Long-term prognostic value of high-sensitivity troponin T added to N-terminal pro brain natriuretic peptide plasma levels before valve replacement for severe aortic stenosis

The American Journal of Cardiology Nov 09, 2019

Barbieri F, Senoner T, Adukauskaite A, et al. - Researchers examined a large cohort undergoing either surgical (57.8%) or transcatheter (42.2%) aortic valve replacement, to compare the additive preprocedural value of high-sensitivity troponin T (hsTnT) to N-terminal pro brain natriuretic peptide (NT-proBNP) plasma concentrations in predicting long-term survival after the operation. Death of 919 patients (25.6%) was reported during a median follow-up of 2.93 years; of these, cardiovascular causes were responsible for 556 (15.5%) deaths. They found that as far as postoperative survival in patients with severe aortic stenosis (AS) admitted for valve replacement was concerned, hsTnT added additional influence to NT-proBNP as a routinely accessible biomarker for risk stratification. The idea to combine hsTnT plasma levels in the management of severe AS was supported.
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