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Long-term patterns of cancer incidence among patients with and without type 2 diabetes in the United Kingdom

Diabetes Research and Clinical Practice Feb 05, 2022

According to findings, type 2 diabetes is linked with an elevated risk of several cancers.

  • Using the United Kingdom Clinical Practice Research Datalink, a total of 890,214 patients with type 2 diabetes were matched to an equal number of patients without type 2 diabetes in this large population-based study.

  • A higher cancer incidence was found in patients with type 2 diabetes vs patients without type 2 diabetes (incidence rate ratio, IRR: 1.19, 95% CI 1.18-1.21).

  • The IRR was higher 2010 onwards (IRR: 1.25, 95% CI: 1.23-1.28) than the association in previous years.

  • A 5% higher incidence of being diagnosed with multiple cancers was present in type 2 diabetes patients (IRR: 1.05, 95% CI: 1.04-1.07).

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