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Long-term outcomes of cognitive behavioral therapy for anxiety-related disorders: A systematic review and meta-analysis

JAMA Psychiatry Dec 07, 2019

van Dis EAM, van Veen SC, Hagenaars MA, et al. - Researchers investigated the long-term outcome of cognitive-behavioral therapy (compared with care as usual, relaxation, psychoeducation, pill placebo, supportive therapy, or waiting list) for anxiety disorders, posttraumatic stress disorder, and obsessive-compulsive disorder via performing a systematic review and meta-analysis of 69 randomized clinical trials including 4,118 patients. The outcomes revealed the relation of cognitive-behavioral therapy with better outcomes relative to control conditions among patients with anxiety symptoms within 12 months after treatment completion. They identified significant correlations only for generalized anxiety disorder, social anxiety disorder, and posttraumatic stress disorder at longer follow-up. After 3 to 12 months, relapse rates (predominantly for panic disorder with or without agoraphobia) were 0% to 14%.
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