Prabhasawat P, Chotikavanich S, Ngowyutagon P, et al. - In this retrospective, interventional case series, researchers sought to assess the long-term outcomes, anatomical retention, and complications of Boston type I keratoprosthesis (KPro). Risk factors for anatomical retention and functional success have been analyzed. Participants in the study were 26 patients (27 eyes). Failed penetrating keratoplasties were the most common indication for KPro surgery. Data reported that the anatomical retention rate was 88.9%, and the functional success rate was 44.4%. Retroprosthetic membrane formation and infection were the most common complications. With its high retention rate and positive visual outcomes, Boston type I KPro could be an alternative treatment for patients with conventional PKP failure, particularly when combined with careful patient selection and complication prevention. Standard prophylactic antibiotics combined with topical 0.1% amphotericin B and 5% povidone iodine may be an effective infection prevention strategy, particularly in tropical countries.