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Long-term outcomes after disease activity-guided dose reduction of TNF inhibition in rheumatoid arthritis: 3-year data of the DRESS study - A randomised controlled pragmatic non-inferiority strategy trial

Annals of Rheumatic Diseases Sep 20, 2017

Bouman CAM, et al. - The long-term outcomes of TNFi DR in RA by utilizing 3-year data from the DRESS study (Dose REduction Strategy of Subcutaneous TNF inhibitors study) are evaluated in this study. Safety and effectiveness of disease activity guided TNFi DR in RA are maintained up to 3 years, with a large reduction in TNFi utilization, but no other benefits. Implementation of DR would vastly improve the cost-effective utilization of TNFi.
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