Wang H, et al. - In this study including 75 atrial septal defect (ASD) patients with atrial tachyarrhythmia (ATa, 52% atrial fibrillation, AF), researchers determined the efficacy, safety, and long-term outcome of radiofrequency catheter ablation (RFCA). They carried out an electrophysiological study and RFCA, with endpoints of index and multiple procedures as follows: atrial tachycardia/ atrial flutter (AT/AFL), absence of inducibility of any atrial arrhythmia and AF, circumferential pulmonary vein ablation (CPVA, paroxysmal AF), bidirectional block of lines, and disappearance of complex fractionated atrial electrograms (persistent and long-standing persistent (LSP)-AF). One-year follow-up revealed a 79.9% cumulative success rate, which dropped to 59.0% at a median follow-up of 63 months (range, 14–114 months) for multiple procedures (mean 1.6 ± 0.7 [1–3]). In 75% of patients with AT/AFL and 43.6% of patients with AF, no ATa was reported after multiple procedures. Overall, a favorable long-term outcome of RFCA for ATa was reported for AT/AFL while for AF, outcomes were average. Significant independent predictors of ATa recurrence in multivariate analysis were older age at ASD correction, ASD diameter prior to correction, and first-diagnosed AF. A higher risk of ATa recurrence was seen in patients with more risk factors.