Long-term mortality risk associated with citric acid- and acetic acid-based bicarbonate haemodialysis: A historical cohort propensity score-matched study in a large, multicentre, population-based study
Nephrology Dialysis Transplantation Aug 13, 2020
Neri L, Bellocchio F, Kircelli F, et al. - Given that a higher death hazard in haemodialysis (HD) clinics with high citric acid-based bicarbonate dialysate (CiD) consumption has been reported in a French ecological study, thus raising safety concerns over CiD, so, researchers assessed the death risk related to various acidifiers (AcD, CiD) of bicarbonate dialysate in this multicentre, historical cohort study. Adult incident HD patients were involved and propensity score matching was applied. In a large European cohort of dialysis patients, increased mortality was not evident in patients exposed to CiD, although physicians more tended to prescribe CiD to individuals with worse medical conditions.
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