Gorriz JL, D’Marco L, Pastor-González A, et al. - Researchers performed this retrospective observational study to assess the link between the trajectory of potassium measurements and long-term all-cause death in patients experiencing acute hyperkalemia. Participants were acute severe hyperkalemia (K > 6 mEq/L) cases without hemolysis. In 160 patients in the emergency room, 172 episodes of acute hyperkalemia were identified. Chronic kidney disease (71.2%), heart failure (35%) and diabetes mellitus (56.9%) were reported as the most frequent comorbidities. Patients receiving chronic dialysis were 11.9% of the total study sample. Mortality was not predicted by the potassium levels before a severe hyperkalemic event. Serial kinetic of potassium trajectories, after an episode of acute severe hyperkalemia, was identified to be predictive of the risk of death. There is a requirement of further evidence to corroborate these observations and to clarify the optimal long-term management of these patients.