Bagger M, et al. - Authors evaluated the risk of metastatic disease after biopsy of posterior uveal melanoma. They recorded detailed information on age, gender, tumor characteristics, and diagnostic and therapeutic measures, including tumor biopsy, if any, and the primary treating hospital for each patient. Findings suggested similarity of all-cause and melanoma-specific mortality after primary treatment among biopsied and nonbiopsied patients with posterior uveal melanoma. An increased metastatic risk after intraocular tumor biopsy is not supported in the findings. At diagnosis, better prognostic characteristics, including smaller tumor size and younger age was demonstrated by biopsied patients than nonbiopsied patients.