Long-term impact of thrombus aspiration in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention
The American Journal of Cardiology Mar 11, 2020
Qin X, Luo J, Qin L, et al. - Among ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI), researchers focused on the impact of adjunctive thrombus aspiration (TA) on long-term results. They performed a retrospective analysis of all Chinese patients with STEMI from the TOTAL trial who were aged ≥ 18 years and were referred for PPCI within the 12 hours following symptom onset between Jan 2011 and Nov 2012. This study involved 563 patients. At 5 years, the estimated incidence rate of major adverse cardiac events in the TA group was found to be similar to that in the PCI group. A significant link of TA with an approximately 7-fold elevated risk of stroke was observed at 5 years, relative to PCI alone. Based on the findings, it was concluded that TA was not related to improved outcomes among STEMI patients but may have an adverse influence on stroke. TA could be beneficial for patients with an occluded infarct-related artery.
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