Tanaka K, Yamanaga S, Hidaka Y, et al. - This single-center retrospective study with 183 living kidney donors was undertaken to assess the link between preoperative serum uric acid (UA) concentrations and post-donation long-term events and kidney function. The participants were split into high (≥ 5.5 mg/dl) and low (< 5.5 mg/dl) UA groups. Over 5 years, 52 adverse events occurred in 44 donors. The high UA group vs the low UA group was found to have significantly higher incidence of adverse events within 5 years; and this remained true even following the exclusion of hyperuricemia-associated events. Lower estimated glomerular filtration rates (eGFRs) post-donation were found in donors with higher UA concentrations, whereas eGFR remained uninfluenced by body mass index, hemoglobin A1c, blood pressure, and low-density lipoprotein cholesterol. Based on the findings, experts recommend considering preoperative UA levels during donor selection as well as postoperative follow-up.