Long-term follow-up of quiescent choroidal neovascularisation associated with age-related macular degeneration or pachychoroid disease
British Journal of Ophthalmology Nov 08, 2019
Forte R, et al. - Researchers retrospectively reviewed 67 eyes (65 patients, 43 females, mean age 76.63±9.7 years) with quiescent type 1 choroidal neovascularisation (CNV) and a minimum follow-up of 12 months at the Department of Ophthalmology of University Paris Est, Creteil and at the Centre Ophtalmologique de l’Odeon, Paris, between June 2009 and December 2018 in order to evaluate the long-term progression of quiescent type 1 CNV associated with age-related macular degeneration or with pachychoroid disease. For quantitative analyses of CNV status biomarkers (fractal dimension, lacunarity, vessel density, aspect ratio, CNV area) they evaluated optical coherence tomography angiography (OCT-A) of eyes not showing CNV activation during 24 months. In the long-term follow-up, an increase of CNV area without significant changes of the other OCT-A biomarkers was observed in inactive quiescent CNV. Greater response to IVI was observed in quiescent type 1 CNV undergoing activation when associated with pachychoroid.
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