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Long-term efficacy of Mitomycin C augmented trabeculectomy in a mixed pediatric glaucoma cohort

Journal of Glaucoma Apr 08, 2021

Gurney SP, Ahmad M, Makanjuola T, et al. - Researchers sought to assess the long-term effectiveness and safety of Mitomycin C-augmented trabeculectomy in a mixed, tertiary-referral, pediatric glaucoma cohort. Between 2008 and 2016, retrospective consecutive review of all children (37 eyes) undergoing Mitomycin C-augmented trabeculectomy by a single surgeon. Overall, trabeculectomy was effective in 80.6% of eyes at 12 months, 60.5% at 3 years, and 57.5% at 5 years. This study adds to the growing body of evidence that Mitomycin C-augmented trabeculectomy is a safe and effective treatment for primary or secondary pediatric glaucoma, with particularly promising results in cases of secondary glaucoma. In a significant proportion of children, trabeculectomy has the potential to postpone or avoid glaucoma drainage device surgery.

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