Diez-Cirarda M, et al. - The longitudinal effects of a 3-month cognitive rehabilitation program evaluating the cognitive, behavioural and neuroimaging changes after 18 months were assessed. The authors proposed that despite the structural brain changes, the improved cognitive performance and the increased brain functional connectivity (FC) and activation after cognitive rehabilitation were significantly maintained after 18 months in Parkinson's disease (PD) patients consistent with a progression of neurodegenerative processes.