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Long-term effects of citric acid-based bicarbonate haemodialysis on patient outcomes: A survival propensity score–matched study in western France

Nephrology Dialysis Transplantation Aug 13, 2020

Potier J, Dolley-Hitze T, Hamel D, et al. - This population-based retrospective multicentre observational study was undertaken to evaluate the long-term impacts of citric acid–based bicarbonate haemodialysis (CIT-HD) exposure on patient results in western France. This analysis involved 1,132 incident end-stage kidney disease patients who initiated their renal replacement therapy after 1 January, 2008 and observed through 15 October, 2018. Propensity score matching at 2:1 was done in two steps in order to provide a control group to CIT-HD one. Based on the findings, the notion that CIT-HD exposure ≤ 6 years has no significant impact on all-cause death in HD patients was supported. This result is true for patients undergoing high-volume online haemodiafiltration, a modality most often prescribed in this cohort.

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