Karagiannis D, et al. - This study was performed to assess the anatomical and functional outcomes in patients with submacular hemorrhage (SMH) due to age-related macular degeneration (AMD) treated with ranibizumab, and to evaluate the potential role of the SMH location in the final outcome after treatment. Findings suggested intravitreal ranibizumab as safe and effective in terms of either improving or stabilizing visual acuity, in patients with SMH due to wet AMD. The location of the SMH seemed predictive of the final outcome after treatment.