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Lipodystrophy and obesity are associated with decreased number of T cells with regulatory function and pro-inflammatory macrophage phenotype

International Journal of Obesity Aug 17, 2017

Berger S, et al. – This study was carried out to assess whether T–cell populations with regulatory function and monocyte–derived macrophages (MDMs) are affected by LD and obesity. The results of this study displayed that LD and obesity are correlated with changes in the immune system: a significant reduction in the number of T cells with regulatory function and a shift of MDM towards lipid accumulation. Lipid profile of the patients associates with these alterations.
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