de Oliveira Figueiredo RA, Kajantie E, Neuvonen PJ, et al. - Since early and repeated exposure to antimicrobial agents (AMs) in infancy is correlated with increased risk of childhood overweight and obesity, researchers extended the investigation of AMs use, from birth to early adolescence, and assessed their connection with weight status. In total, 10,093 children from Finnish Health in Teens cohort (Fin‐HIT) with register‐based data on AMs purchases and measured weight status at the mean age of 11.2 y (SD 0.82) were involved in the analysis. The highest prevalence of AMs use occurred during the first 2 years of life and thereafter decreased with age in children in this cohort study with registry‐based medical purchase history. Despite a high prevalence of AMs use during the early years, lifetime‐use was linked to weight status in early adolescence in a dose response manner. Mechanisms underlying the relationship between AM usage and weight should be discussed in future studies.