Chen H, et al. - Researchers analyzed a contemporary cohort of Autosomal Dominant Polycystic Kidney Disease (ADPKD) patients in order to determine the prevalence of left ventricular hypertrophy (LVH) applying consensus echocardiography criteria and to assess the independent link of ADPKD severity with LV mass in these patients. A single-center study was undertaken to inquire 126 adults with ADPKD and eGFR > 15 ml/min/1.73m² (78% with hypertension, median age was 46 years). The estimated prevalence of LVH was 21.4% as defined by left ventricle mass index. Participants with hypertension (HTN) vs without HTN had no significantly different LVH prevalence and the prevalence was similar (21.4%) following the elimination of those (N = 21) with recognized cardiac disease. Findings revealed a high prevalence of LVH in this contemporary cohort involving ADPKD patients with well-controlled blood pressure. Also, an independent link of ADPKD severity, as indicated by total kidney volume, with greater LV mass was also revealed. A link between ADPKD pathophysiology and increased LV mass may be indicated.