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Left ventricular assist devices in pulmonary hypertension Group 2 with significantly elevated pulmonary vascular resistance: A bridge to cure

Heart, Lung, and Circulation May 28, 2018

Selim AM, et al. - Researchers reviewed the records of left ventricular assist devices (LVAD) patients in their institution, to determine if LVAD has a favourable impact in advanced pulmonary arterial bed disease with a significant elevation in pulmonary vascular resistance. They found that pulmonary haemodynamic parameters significantly improved post LVAD placement in all patients. They also observed that in a subgroup of patients who underwent cardiac transplantation post LVAD, all patients maintained a normalised pulmonary vascular resistance (PVR) [<3 Wood units (WU)] one year post-HTx. Overall, pulmonary hypertension WHO Group 2 with significantly elevated PVR can be reversed with the use of left ventricular assist devices; this impact was not dependent on the baseline PVR, and was maintained up to one year post cardiac transplantation.
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