Andrilla CHA, et al. - Using logistic regression, researchers investigated the extent to which the United States’ rural residents vs nonrural residents present at a more advanced stage of colorectal cancer (CRC). The 2010–2014 Surveillance, Epidemiology and End Results Incidence data was utilized for this purpose and the link between late stage at diagnosis and county-level features was assessed. They found a link between geographic residence and the rate of stage 4 disease at presentation. The highest rate of stage 4 disease was observed in patients residing in remote small rural counties. Findings also revealed the link of additional patient factors with stage 4 CRC disease at diagnosis. Worse cancer outcomes were reported in rural patients, and this disparity may be partially attributable to late stage at diagnosis. The persistence of these differences over time has been reported.