Owrangi B, et al. - Researchers here aim to test the hypothesis that in hospitalised patients, uropathogenic Escherichia coli (UPEC) strains might translocate from the gut to the blood stream and that this could be due to the presence of virulence genes (VGs) that are not commonly found in UPEC strains that cause urinary tract infection (UTI) only. Findings suggested that UPEC strains are capable of translocating through gut epithelium, irrespective of their source. However, compare to CA-UPEC, urosepsis and HA-UTI strains are observed to have a much better ability to interact with gut epithelia and have a greater virulence potential, which allows them to cause blood infection.