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Intrinsic wave propagation of myocardial stretch, a new tool to evaluate myocardial stiffness: A pilot study in patients with aortic stenosis and mitral regurgitation

Journal of the American Society of Echocardiography Aug 25, 2017

Pislaru C, et al. – The goal of this research was to investigate the hypothesis that intrinsic velocity propagation of myocardial stretch (iVP) would be changed in patients with valvular disease and chronic left ventricular (LV) pressure overload or volume overload, which may adversely affect mechanical properties of the LV tissue. They exhibited evidence that a significant number of patients with severe Aortic stenosis and severe mitral regurgitation (MR) had rapid transmission of myocardial stretch, indicating increased myocardial stiffness. This information was not conveyed by measurement of flow propagation. Larger studies are required to evaluate the clinical utility of this novel measurement.
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