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Intradermal band-like lipomatous metaplasia can be associated with the regression of overlying skin neoplasms: A clinicopathologic study of 20 cases

The American Journal of Dermatopathology Jun 28, 2021

Takai T, et al. - Researchers conducted the study for analyzing the characteristics and relationship of intradermal band-like lipomatous metaplasia and coexisting skin tumors. In total, 20 cases with intradermal band-like lipomatous metaplasia were retrieved from 10,992 archive cases at Hyogo Cancer Center between April 1997 and March 2020 and subjected to a detailed clinicopathologic analysis. All 20 cases exhibited at least one of three signs of tumor regression: partial loss of overlying neoplasia, significant inflammatory infiltrate under the tumor, and fibrosis surrounding the tumor. The findings suggested that intradermal band-like lipomatous metaplasia could occur in conjunction with the regressing process of cutaneous superficially-spreading neoplasms.

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