Ibrahim HN, Murad DN, Hebert SA, et al. - Because of the correlation of obesity with the two archetypal kidney disease risk factors: hypertension and diabetes, concerns have been raised that in obese kidney donors, the effects of diabetes and hypertension might be magnified in their remaining kidney and have resulted in the exclusion of many obese candidates from kidney donation.

• Comparison in terms of mortality, diabetes, hypertension, proteinuria, reduced eGFR and its trajectory, and the development of kidney failure was done in 8,583 kidney donors, according to BMI.

• Similar to the general population, kidney donors showed the correlation of obesity with raised risk of developing diabetes, hypertension, and proteinuria.

• Obese donors were similar to non-obese donors in terms of mortality.

• In non-obese, obese, and very obese donors, absolute risks of ESKD were 0.5%, 0.7%, and 0.9%, respectively (BMI < 30 kg/m², ≥ 30 kg/m², or > 35 kg/m², respectively).

• Based on findings, researchers emphasize considering judicious acceptance of obese but otherwise healthy donor candidates.