Inpatient morbidity and mortality of measles in the United States
PLoS Neglected Tropical Diseases May 01, 2020
Chovatiya R, et al. - In the US, measles was officially declared eradicated in 2000. However, measles outbreaks are increasingly occurring in the US leading the researchers to determine the frequency, predictors, costs and other outcomes of hospitalization for measles in the US. They performed analysis of the 2002–2016 Nationwide Inpatient Sample, containing a 20% sample of US hospitalizations (n = 96,568,625) and identified overall, 1,018 measles hospitalizations during this period. They observed that a substantial and preventable healthcare burden is posed by measles with serious complications, hospitalization and inpatient mortality. Per multivariable logistic regression models, higher odds of gastrointestinal, hematologic, infectious, neurologic, ophthalmologic, pulmonary, and renal complications were observed in correlation with measles; the strongest association was observed with encephalitis. They observed increased length of stay and similar cost of care vs all other admissions. Numerically higher inpatient mortality was reported in those with vs without measles.
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