Marsidi AM, Kipling LM, Kawwass JF, et al. - In this retrospective cohort study, researchers sought to describe paternal age among assisted reproductive technology (ART) cycles performed in the United States and to assess the influence of paternal age on ART cycles and perinatal outcomes. All reported fresh, nondonor, noncancelled in vitro fertilization (IVF) cycles conducted in 2017. The primary outcomes were intrauterine pregnancy, live birth (≥ 20 weeks), and miscarriage (< 20 weeks) per cycle start and per embryo transfer, whereas the secondary outcomes were full-term live birth (≥ 37 weeks) among singleton and twin gestations. Compared with paternal age ≤ 45 years, paternal age ≥ 46 years is linked to a lower probability of pregnancy and live birth among couples undergoing IVF. Since maternal age is a stronger predictor of ART outcome, the negative impact of paternal age is most noticeable among women aged ≥ 35 years.