Vu CHV, et al. - The impact of meibomian gland dysfunction (MGD) and friction-related disease (FRD) on the severity of dry eye disease (DED) was determined. Findings demonstrated associations between MGD, FRD, or both and ocular signs in DED. Additionally, it was also noted that tear film breakup time was significantly shortened regardless of the dry eye status or subtype, in the presence of MGD, FRD, or both.