Rooney SR, Mastropietro CW, Benneyworth B, et al. - Given that early extubation after pediatric cardiac surgery is common, but it is not clear if the outcome is impacted by the location (operating room or cardiac ICU), therefore, researchers undertook this secondary analysis of the Pediatric Cardiac Critical Care Consortium registry to analyze early extubation practice variation across hospitals as well as to determine how location impacts hospital length-of-stay as well as other outcomes. Overall 28 Pediatric Cardiac Critical Care Consortium hospitals participated. Hospitals were grouped depending on the proportion of their early extubation patients who received an odds ratio extubation. More use of noninvasive ventilation and fewer extubation failures were reported for high-frequency odds ratio early extubation hospitals vs low-frequency hospitals. Findings demonstrated the presence of considerable variability in early extubation practices following low- and moderate-complexity pediatric cardiac surgery. No significant difference in hospital length-of-stay was observed between centers with different early extubation strategies based on location or frequency.