Skorpen CG, et al. - The authors aimed to evaluate the relationship between disease activity and medications with offspring birth weight, pre-eclampsia and preterm birth in systemic lupus erythematosus (SLE). Results demonstrated that the SLE had increased chances of the low birth weight and preterm birth, which was increased by the active disease. In case of the active disease, but not inactive disease, the chances of pre-eclampsia were increased. A tight follow-up targeting inactive disease before and during the pregnancy was required.