Santoro F, et al. - Researchers used propensity score matching to compare circulating cytokine levels during the acute and subacute phase of Takotsubo cardiomyopathy (TTC) and acute coronary syndrome (ACS). At admission (t₀) and after 120 h (t₁), they recorded clinical baseline features and circulating levels of interleukin(IL)-1β, IL-1α, IL-2, IL-4, IL-6, IL-8, IL-10, IFN-γ, MCP1, EGF, VEGF, TNFα. Findings suggested that the acute phase of TTC could be characterized by increased levels of anti-inflammatory interleukins while ACS by higher levels of IL-6 during the acute and sub-acute phase. Overall, during the acute and subacute phase of TTC, different inflammatory patterns can be observed, relative to ACS.