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Infant weight growth patterns, childhood BMI, and arterial health

Obesity Feb 15, 2022

Childhood may be the origin of the associations of obesity with cardiovascular disease. Researchers sought to investigate critical periods for BMI in relation to arterial health at school age.


From a prospective cohort study, researchers assessed 4,731 children for the correlations of infant peak weight velocity, both age and BMI at adiposity peak, and BMI trajectories with carotid artery intima-media thickness and carotid artery distensibility at 10 years.

  • Analysis revealed higher intima-media thickness and lower distensibility at 10 years in correlation with a 1-standard deviation score (SDS) higher peak weight velocity and BMI at adiposity peak.

  • Correlation of infant weight growth patterns and childhood BMI was observed with subtle disparities in carotid intima-media thickness and carotid distensibility at school age.

  • Current BMI appears critical for distensibility.

  • There is a necessity for follow-up to ascertain if these correlations result in adult cardiovascular disease.

 

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