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Independent and synergistic effects of high blood pressure and obesity on retinal vasculature in young children: The Hong Kong Children Eye Study

Journal of the American Heart Association Jan 29, 2021

Ho A, Cheung CY, Wong JS, et al. - Researchers assessed the independent as well as synergistic impacts of hypertensive blood pressure (BP) and obesity on retinal vasculature among young children. From the Hong Kong Children Eye Study, they recruited 1,006 children aged 6 to 8 years. The narrowest central retinal arteriolar equivalents were detected in children with hypertensive systolic BP vs children with either increased or normotensive systolic BP. Narrower central retinal arteriolar equivalents, wider central retinal venular equivalents, and reduced arteriolar fractal dimensions were observed in relation to increased standardized systolic BP. The smallest arteriolar fractal dimensions were found in children with obesity vs children with overweightness and normal weight. Overall, results showed the potential synergistic or additive impacts for both hypertensive BP as well as obesity on retinal vasculature in this pediatric population.

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