Increasing mixed venous oxygen saturation is a predictor of improved renal function after balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension
Heart and Vessels Nov 05, 2018
Isobe S, et al. - In patients with pulmonary hypertension, renal function has been recognized as a prognostic indicator, so researchers assessed clinical parameters related to improved renal function in 45 consecutive patients (mean age 62.2 ± 15.1 years) undergoing balloon pulmonary angioplasty (BPA) for inoperable chronic thromboembolic pulmonary hypertension (CTEPH). At baseline and at 1-year post-BPA, patients’ clinical characteristics were assessed; the link between renal function and hemodynamic parameters, including right heart function were also evaluated. Up to the chronic phase, improvements were seen in symptoms, right heart function, hemodynamics, and renal function, with BPA. For improving renal function 1 year in CTEPH patients following BPA, it was crucial to increase mixed venous oxygen saturation by >125.4% above baseline in the acute phase.
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