Increasing BMI is associated with both endometrioid and serous histotypes among endometrial rather than ovarian cancers: A case-to-case study
Gynecologic Oncology Jun 25, 2019
Grandi G, et al. - Researchers conducted this retrospective case-to-case study to assess if BMI plays a part in carcinogenesis of endometrioid and the serous malignancies, at both ovarian and endometrial level. For this investigation, 1,052 women diagnosed with EC (n=897 endometrioid, n=52 serous) and 955 women with OC (n=132 endometrioid, n=627 serous) were included. EC patients vs women diagnosed with OC had higher median BMI. A one unit increase in BMI was linked to a 5% higher odds of endometrial vs ovarian cancer after controlling for confounding. Among both serous and endometrioid histotypes, increasing BMI was related to endometrial rather than ovarian cancer.
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