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Increased risk of death in first year after liver transplantation among patients with nonalcoholic steatohepatitis vs liver disease of other etiologies

Clinical Gastroenterology and Hepatology Apr 25, 2019

Nagai S, et al. - Via analyzing data from the United Network for Organ Sharing registry, researchers compared outcomes of subjects with liver diseases of different etiologies (non-alcoholic steatohepatitis [NASH], hepatitis C virus [HCV]-associated liver disease, and alcohol-associated liver disease [ALD]). The study sample consisted of 6344 patients who underwent liver transplantation for NASH, 17,037 for cirrhosis from chronic HCV infection, and 9279 for ALD. According to findings, the risk of death within 1 year after transplant was higher among patients with NASH than HCV-associated liver disease or ALD in an analysis of data from patients who had liver transplantation during 2016–2017. Death risk increased with age and a higher risk of death from cardiovascular or cerebrovascular disease is present in patients with NASH.
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