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Increased risk of benign paroxysmal positional vertigo in patients with non-apnea sleep disorders: A nationwide, population-based cohort study

Journal of Clinical Sleep Medicine Dec 20, 2018

Shih CP, et al. – Using the Taiwan National Health Insurance Research Database from 2000 to 2013, researchers assessed the link between non-apnea sleep disorders (NSD) and subsequent benign paroxysmal positional vertigo (BPPV) risk in this retrospective cohort study involving over 120,000 individuals. Study participants were divided into two groups: an NSD group (n=24,624) and an age-, sex-, and index year-matched control group (n=98,496). The main measure was BPPV occurrence. The investigators compared BPPV incidence rates between the two cohorts with a 14-year follow-up. They used Cox proportional hazards regression analysis to evaluate the impact of NSD on the risk of BPPV. They observed a significant increase in the risk of BPPV by NSD by 2.357- to 3.658-fold in cases with hypertension, diabetes mellitus, chronic obstructive pulmonary disease, and hyperlipidemia. They found the highest risk of BPPV in study participants with chronic insomnia, followed by organic sleep disorders, sleep disturbance, and acute insomnia.

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