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Including 60 mg elemental iron in a multiple micronutrient supplement blunts the increase in serum zinc after 12 weeks of daily supplementation in predominantly anemic, nonpregnant cambodian women of reproductive age

The Journal of Nutrition Aug 02, 2019

Holmes JB, Kroeun H, Houghton LA, et al. - In a 2 × 2 factorial, double-blind, randomized, 12-week trial, researchers studied the impact of multiple micronutrient (MMN) supplementation with or without iron-on serum zinc, selenium, and copper concentrations in Cambodian women (n = 760). For this investigation, predominantly anemic, nonpregnant women aged 18 to 45 years received 60 mg of iron daily. Investigators found that the inclusion of 60 mg of iron in Cambodian women's daily MMN formulation may interfere with the absorption and/or metabolism of supplemental zinc. This is particularly worrying when supplementation with MMN is implemented in populations at risk of zinc deficiency.

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