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Incidence, hospitalization and mortality and their changes over time in people with a first ever diabetic foot ulcer

Diabetic Medicine Oct 22, 2021

Røikjer J, Werkman NCC, Ejskjaer N, et al. - This study of diabetic patients in the UK primary care CPRD GOLD database (2007-2017) revealed decline in all incidence rates (IRs) of the first diabetic foot ulcers (DFUs) as well as in hospitalizations and mortality in people with type 2 diabetes. This indicates improved prevention and care of the first DFU for this group in primary care in the UK.

  • This study involved 129,624 persons with diabetes from the abovementioned database, DFUs were identified using Read codes and expressed as IRs.

  • For people with type 2 diabetes and for those with type 1, the mean IR of first registered DFUs was 2.5 per 1,000 person-years and 1.6 per 1,000 person-years, respectively.

  • Reduction in IRs was evident for persons with type 2 diabetes (incidence rate ratio: IRR per year: 0.97), there were no changes for those with type 1 diabetes (IRR per year: 0.96).

  • In type 2 diabetes patients, average hospitalization and 1-year mortality-risk were 8.2% and 11.7%, respectively, and both showed reduction over time (odds ratios: 0.89 and 0.94).

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