Jiang Y, Boris AF, Zhu Y, et al. - A new term, mid-range left ventricular ejection fraction (mrEF) heart failure, was introduced in the 2016 European Society of Cardiology Guidelines. Researchers aimed at determining the clinical characteristics and short-term outcomes in cardiogenic shock patients with mrEF after acute myocardial infarction.

• Researchers performed a retrospective analysis of the baseline characteristics, management, and outcomes according to the left ventricular ejection fraction (LVEF), reduced LVEF (rEF) ≤ 40%, mrEF 41% to 49%, and preserved LVEF (pEF) ≥ 50% in patients with acute myocardial infarction complicated by cardiogenic shock.

• A total of 218 patients were analyzed; these comprised 71 (32.6%) with mrEF.

• After multivariable adjustment, comparable 30-day all-cause mortality was recorded for patients with mrEF vs rEF, and pEF was linked with reduced risk of 30-day all-cause mortality compared with rEF.

• In contrast, there was a lower risk of 30-day MACE in mrEF and pEF than that of rEF.

• Overall in patients with mrEF, the clinical characteristics and short-term mortality were inclined to that of rEF and there was a prognostic significance of occurrence of early left ventricular systolic dysfunction.