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Incidence and mortality of healthcare-associated infections in hospitalized patients with moderate to severe burns

Journal of Critical Care Aug 30, 2019

Chen YY, et al. - Researchers conducted prospective surveillance in a medical center from 2005 through to 2016 in order to assess the incidence of different types, and isolated pathogens, of healthcare-associated infections (HAIs). Further, they sought to determine their prognostic factors for mortality. Hospitalization of a total of 709 patients with moderate to severe burns, was reported. They identified 83 patients (11.7%) who had HAIs (158 episodes) and isolated 203 pathogens. Bloodstream infection (BSI) were identified to be the most common types of healthcare-associated infections. Central line–associated BSI being the highest incidence density of all device–associated infection types (mean 4.8 per 1000 central line days). Overall, the most isolated pathogens and multidrug-resistant pathogen were S. aureus (13.8%) and carbapenems–resistant Enterobacteriaceae (23%), respectively. The crude mortality rate of 15.7% was observed. BSI (OR 2.70), ICU (OR 5.19) and TBSA with full-thickness injuries ≥ 50% (OR 5.22) were the significant prognostic factors of mortality.
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