In-hospital and 1-year mortality trends in a national cohort of US veterans with acute kidney injury
Clinical Journal of the American Society of Nephrology Feb 09, 2022
Findings demonstrate a high AKI-associated mortality, as greater than one in four patients with AKI died within 1 year of hospitalization. Over the past decade, no significant progress appears to have occurred toward improving in-hospital or long-term AKI survivorship.
In this retrospective cohort study utilizing data on 1,688,457 patients and 2,689,093 hospitalizations from the national Veterans Health Administration, the trends in in-hospital and 1-year mortality linked with AKI as defined by Kidney Disease Improving Global Outcomes consensus criteria were analyzed.
Of AKI patients, in-hospital deaths occurred in 6%, and death occurred within 1 year in 28%.
In non-AKI hospitalizations, in-hospital and 1-year death rates were 0.8% and 14%, respectively.
A slight decrease in crude in-hospital AKI-associated mortality (hazard ratio, 0.98 per year) was observed during the study period, that was attenuated post-accounting for patient demographics, comorbid conditions, and acute hospitalization features (adjusted hazard ratio, 0.99 per year).
Persistence of this stable temporal trend in mortality was noted at 1 year (adjusted hazard ratio, 1.00 per year).
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