Improvement in ocular symptoms and signs in patients with Demodex anterior blepharitis using a novel terpinen-4-ol (2.5%) and hyaluronic acid (0.2%) cleansing wipe
Clinical Ophthalmology Jun 25, 2019
Messaoud R, et al. - After using a novel cleansing wipe impregnated with 2.5% terpinen-4-ol and 0.2% hyaluronic acid, researchers assessed the clinical improvement in ocular symptoms and signs in patients suffering from Demodex anterior blepharitis. For this exploratory, multicenter, open, randomized, two-parallel group comparative study, 48 patients with Demodex anterior blepharitis were randomly assigned to apply the sterile wipe T1172 (Blephademodex®), either once daily (n=24, Group 1) or twice daily (n=24, Group 2) for 29 days. According to findings, daily eyelid hygiene with this cleansing wipe impregnated with 2.5% terpinen-4-ol and 0.2% hyaluronic acid over a 4-week period resulted in a fast and marked decrease in ocular symptoms and signs related to Demodex anterior blepharitis and was well tolerated. All patients have been satisfied or very satisfied and will continue to use it.
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