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Importance of supplemental patch testing beyond a screening series for patients with dermatitis

JAMA Dec 18, 2021

Warshaw EM, Buonomo M, DeKoven JG, et al. - According to findings, it is necessary to perform comprehensive patch testing with more than 70 allergens, including supplemental series and personal and work materials, in order to properly identify allergens and successfully manage allergic contact dermatitis.

  • This cross-sectional study including 43,417 patients with dermatitis was conducted to characterize patients who exhibited clinically relevant patch test findings to supplemental (nonscreening) allergens or substances.

  • Of patients who underwent patch testing to an allergen screening series of 65 to 70 allergens, at least 1 relevant reaction to supplemental allergens/substances was evident in 21.9%.

  • Of these, one-quarter showed reaction only to a supplemental allergen/substance.

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